Lab Members

I earned my Diploma in chemistry at the University of Athens, Greece, then trained in synthetic inorganic chemistry and protein crystallography with Professors Dimitri Coucouvanis, Martha Ludwig and Janet Smith at the University of Michigan. I began my independent career at the Uniformed University of the Health Sciences before moving back to the University of Michigan in 2018.

My project revolves around understanding the binding of a minimal RNase P enzyme to pre-tRNA substrates. In my free time, I love to read, play video games, watch TV, practice calligraphy, and spend time with my cats.

I got my BA in chemistry from Macalester College. I'm currently working to understand the cobalamin riboswitch structure and function through x-ray crystallography and assays. For fun, I like to run the trails in Ann Arbor, read books, and explore restaurants in the area with friends.

My project is focused on using Cryo-EM to understand the conformational changes in Methionine Synthase.

I work on understanding the mechanism and substrate recognition of the RNA maturation enzyme PRORP through kinetics assays. I completed my PhD at the University of Michigan under the mentorship of Dr. Carol Fierke, and my BS in Chemistry at Grand Valley State University.

My project uses x-ray crystallography to better understand the metalloenzyme Methionine Synthase.

I aim to use kinetic techniques to better understand the mitochondrial RNase P complex.

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I got my BA in biochemistry & molecular biology at Hastings College. I am currently starting a project investigating alternative conformations of RNA molecules in existing crystallographic densities. Outside of lab I cook, hike, and read fantasy/scifi novels!

My project is focused on the elongator complex comprised of Elp proteins responsible for the modification of uridine at the wobble position of tRNA. This complex has been implicated in cancer, and understanding the structure and function is of great importance in progressing our understanding of cancer pathways. Outside of the lab, I enjoy golfing and baking bread.

I am using a combination of structure and kinetic studies to better understand the substrate specificity of pseudouridine synthase enzymes.

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